Main entry: mediate
Definition: acting through or dependent on an intervening agency
Usage: the disease spread by mediate as well as direct contact
Antonyms: immediate
Definition: having no intervening medium
Antonyms: direct
Definition: direct in spatial dimensions; proceeding without deviation or interruption; straight and short
Antonyms: direct
Definition: straightforward in means or manner or behavior or language or action
Main entry: in-between, mediate, middle
Definition: being neither at the beginning nor at the end in a series
Usage: adolescence is an awkward in-between age; in a mediate position; the middle point on a line
Antonyms: terminal
Definition: being or situated at an end