Synonyms: estrange, alien, alienate, disaffect
Definition: arouse hostility or indifference in where there had formerly been love, affection, or friendliness
Usage: She alienated her friends when she became fanatically religious
Similar words: alter, change, modify
Definition: cause to change; make different; cause a transformation
Usage: The advent of the automobile may have altered the growth pattern of the city; The discussion has changed my thinking about the issue